
产品货号:
Z32708
中文名称:
CBP/EIF4E抗体
英文名称:
Anti-CBP/EIF4E Antibody (Clone#OTI6C3)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CBP/EIF4E Antibody (Clone#OTI6C3) |
指标别名 | CBP;CBP;EIF4E;eIF 4E;eIF 4F 25kDa subunit;EIF4E;EIF4E1;EIF4EL1;EIF4F;mRNA cap binding protein |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | EIF4E |
克隆号 | OTI6C3 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human EIF4E (NP_001959) produced in HEK293T cell. |
实际分子量 | 24.9KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure,m7GpppX (where X is any nucleotide).This structure is involved in several cellular processes including enhanced translational efficiency,splicing,mRNA stability,and RNA nuclear export.EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs.It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F.The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis.The other subunits of EIF4F are a 50-kD polypeptide,termed EIF4A (see MIM 601102),that possesses ATPase and RNA helicase activities,and a 220-kD polypeptide,EIF4G (MIM 600495) (Rychlik et al.,1987 [PubMed 3469651]).[supplied by OMIM] |
Uniprot ID | P06730 |
基因名全称 | eukaryotic translation initiation factor 4E |
蛋白名全称 | Eukaryotic translation initiation factor 4E |
推荐稀释比 | Western blot (WB) 1:500 Immunohistochemistry in paraffin section (IHC) 1:150 |
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